Reliability of Estimation of HBA1C for Diagnosing Gestational Diabetes

Gestation Diabetes mellitus is a condition that, if left untreated, can have adverse effects not only on the mother but also unborn child. Even though oral glucose tolerance test (OGTT), which typical method of screening for gestational diabetes in pregnant women and has been widely used recognised number decades, there still need that both more accurate simpler to administer order diagnose GDM. This case despite fact standard involves an OGTT Subjects Methods: In this prospective observational study, HbA1c were performed 400 antenatal between 24 28 weeks gestation; followed up thereafter. Repeat done with GDM at 6 postpartum. Results: Among women, 52 diagnosed GDM, incidence 9%. The mean level was 6.2 – 0.6%, whereas it 5.4 0.5% those normoglycemia. Women had higher pregnancy-related complications compared normoglycemic women. An cutoff 5.3% sensitivity 95.6% specificity 51.6% diagnosis would avoided approximately half while missing 5% However, abnormal will require confirmatory OGTT, as 50% be misclassified having by approach. On repeat testing postpartum, two (4.4%) overt mellitus, five (11.1%) impaired tolerance. Conclusions: Although cannot replace test, avoiding used. findings all these trials make abundantly evident HbAlc superior than traditional important respects. great reproducibility assay, improved instrumentation standardisation less biological variability, affected short-term changes lifestyle are factors contribute advantages. It possible use primary due patient does prepare significantly takes time. If, other hand, result discovered greater reference range, then absolutely necessary perform establish anticipated able function diagnostic marker not-too-distant future. Keywords: GDM; HbAlc.